Solutions

Product Portfolio

• Oncobit™ DxM

  

  Oncobit™ DxM is a targeted sequencing approach to assess FFPE tissue of advanced melanoma patients.

  Oncobit™ DxM captures:

  • mutations in all melanoma-relevant genes
  • melanoma-relevant gene rearrangements
  • copy number variants (CNV) in a genome-wide manner and chromosomal aneuploidies
  • total tumor mutational burden (TMB)
  • mutation signatures
  • HLA types
  • T-cell receptor (TCR) clonality

  All findings are annotated with a curated knowledge database of approved and off-label therapies and ongoing clinical trials relevant for the respective patient. Results, suggested therapies and trials are summarized in an automatically generated customized report, providing a precise diagnosis of the tumor as well as therapy decision support.

   

• Oncobit™ LBM

  

  Oncobit™ LBM is a targeted sequencing approach to assess blood samples of advanced melanoma patients.

  Oncobit™ LBM captures:

  • mutations in 60 melanoma-relevant genes
  • copy number variants (CNV) in melanoma-relevant genes
  • HLA types

  All findings are annotated with a curated knowledge database to identify non-inheritable genetic alterations. Assessing circulating tumor-derived DNA (ctDNA) isolated from the blood of cancer patients, this method is minimally invasive and provides a comprehensive characterization of cancer and therapy resistance markers in the patient’s blood.

• Oncobit™ PM

  

  Oncobit™ PM allows us to provide highly sensitive monitoring of specific molecular alterations with a short turnaround time. The number and type of alterations evaluated is customized for each patient.

  Similar to Oncobit™ LBM, Oncobit™ PM is a minimally invasive liquid biopsy assay. Oncobit PM represents a tool for personalized monitoring of cancer patients of all types of solid tumors.